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Search Results to Shmuel Yaccoby

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Yaccoby, Shmuel

One or more keywords matched the following items that are connected to Yaccoby, Shmuel

Item Type	Name
Academic Article	Heparanase promotes the spontaneous metastasis of myeloma cells to bone.
Academic Article	Consequences of interactions between the bone marrow stroma and myeloma.
Academic Article	Inhibitory effects of osteoblasts and increased bone formation on myeloma in novel culture systems and a myelomatous mouse model.
Academic Article	Predictive value of alkaline phosphatase for response and time to progression in bortezomib-treated multiple myeloma patients.
Academic Article	Magnetic resonance imaging in multiple myeloma: diagnostic and clinical implications.
Academic Article	The phenotypic plasticity of myeloma plasma cells as expressed by dedifferentiation into an immature, resilient, and apoptosis-resistant phenotype.
Academic Article	Response to bortezomib is associated to osteoblastic activation in patients with multiple myeloma.
Academic Article	Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival.
Academic Article	Targeting beta2-microglobulin for induction of tumor apoptosis in human hematological malignancies.
Academic Article	Human placenta-derived adherent cells prevent bone loss, stimulate bone formation, and suppress growth of multiple myeloma in bone.
Academic Article	Response to bortezomib and activation of osteoblasts in multiple myeloma.
Academic Article	Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo.
Academic Article	Osteoblastogenesis and tumor growth in myeloma.
Academic Article	Role of Bruton's tyrosine kinase in myeloma cell migration and induction of bone disease.
Academic Article	The molecular classification of multiple myeloma.
Academic Article	Highly activated and expanded natural killer cells for multiple myeloma immunotherapy.
Academic Article	Risk factors for MDS and acute leukemia following total therapy 2 and 3 for multiple myeloma.
Academic Article	Role of decorin in the antimyeloma effects of osteoblasts.
Academic Article	Atacicept (TACI-Ig) inhibits growth of TACI(high) primary myeloma cells in SCID-hu mice and in coculture with osteoclasts.
Academic Article	Advances in the understanding of myeloma bone disease and tumour growth.
Academic Article	The SCID-rab model: a novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells.
Academic Article	Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth.
Academic Article	Soluble syndecan-1 promotes growth of myeloma tumors in vivo.
Academic Article	Therapeutic effects of intrabone and systemic mesenchymal stem cell cytotherapy on myeloma bone disease and tumor growth.
Academic Article	Ellipticine derivative NSC 338258 represents a potential new antineoplastic agent for the treatment of multiple myeloma.
Academic Article	The SCID-hu myeloma model.
Academic Article	Characterization of the molecular mechanism of the bone-anabolic activity of carfilzomib in multiple myeloma.
Academic Article	Seven-year median time to progression with thalidomide for smoldering myeloma: partial response identifies subset requiring earlier salvage therapy for symptomatic disease.
Academic Article	Inhibitor of DASH proteases affects expression of adhesion molecules in osteoclasts and reduces myeloma growth and bone disease.
Academic Article	Standard and novel imaging methods for multiple myeloma: correlates with prognostic laboratory variables including gene expression profiling data.
Academic Article	The oxidative stress response regulates DKK1 expression through the JNK signaling cascade in multiple myeloma plasma cells.
Academic Article	The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy.
Academic Article	The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growth.
Academic Article	Consequences of daily administered parathyroid hormone on myeloma growth, bone disease, and molecular profiling of whole myelomatous bone.
Academic Article	Cancer and the microenvironment: myeloma-osteoclast interactions as a model.
Academic Article	Repression of multiple myeloma growth and preservation of bone with combined radiotherapy and anti-angiogenic agent.
Academic Article	A prospective evaluation of the biochemical, metabolic, hormonal and structural bone changes associated with bortezomib response in multiple myeloma patients.
Academic Article	Syndecan-1 is targeted to the uropods of polarized myeloma cells where it promotes adhesion and sequesters heparin-binding proteins.
Academic Article	Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma.
Academic Article	NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity.
Academic Article	The proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivo.
Academic Article	Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression.
Academic Article	Fenretinide inhibits myeloma cell growth, osteoclastogenesis and osteoclast viability.
Academic Article	Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma.
Concept	Multiple Myeloma
Academic Article	Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc3) and bortezomib against multiple myeloma
Academic Article	Role of Bruton's tyrosine kinase (BTK) in growth and metastasis of INA6 myeloma cells.
Academic Article	Ex vivo-expanded natural killer cells demonstrate robust proliferation in vivo in high-risk relapsed multiple myeloma patients.
Academic Article	CYR61/CCN1 overexpression in the myeloma microenvironment is associated with superior survival and reduced bone disease.
Academic Article	Phase II study of pomalidomide in high-risk relapsed and refractory multiple myeloma.
Academic Article	Renal insufficiency retains adverse prognostic implications despite renal function improvement following Total Therapy for newly diagnosed multiple myeloma.
Academic Article	A peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment.
Academic Article	The flow cytometry-defined light chain cytoplasmic immunoglobulin index and an associated 12-gene expression signature are independent prognostic factors in multiple myeloma.
Academic Article	Four genes predict high risk of progression from smoldering to symptomatic multiple myeloma (SWOG S0120).
Academic Article	Primary myeloma interaction and growth in coculture with healthy donor hematopoietic bone marrow.
Academic Article	A Cyclin-Dependent Kinase Inhibitor, Dinaciclib, Impairs Homologous Recombination and Sensitizes Multiple Myeloma Cells to PARP Inhibition.
Academic Article	Monoclonal antibody therapy in multiple myeloma: where do we stand and where are we going?
Academic Article	Dose-dense and less dose-intense Total Therapy 5 for gene expression profiling-defined high-risk multiple myeloma.
Academic Article	Dose-dense and less dose-intense total therapy 5 for gene expression profiling-defined high-risk multiple myeloma.
Academic Article	Adverse Metaphase Cytogenetics Can Be Overcome by Adding Bortezomib and Thalidomide to Fractionated Melphalan Transplants.
Academic Article	Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma.
Academic Article	The prognostic value of the depth of response in multiple myeloma depends on the time of assessment, risk status and molecular subtype.
Academic Article	The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma.
Academic Article	Low expression of hexokinase-2 is associated with false-negative FDG-positron emission tomography in multiple myeloma.
Academic Article	Two States of Myeloma Stem Cells.
Academic Article	The Pattern of Mesenchymal Stem Cell Expression Is an Independent Marker of Outcome in Multiple Myeloma.
Academic Article	The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma.
Academic Article	Mesenchymal stem cells gene signature in high-risk myeloma bone marrow linked to suppression of distinct IGFBP2-expressing small adipocytes.
Grant	Potentiating Natural Killer Cell Anti-Myeloma Effects
Grant	Targeting Dkk1 in multiple myeloma with humanized andti-DKk1 neutralizing antibody
Academic Article	Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma.
Academic Article	PHF19 inhibition as a therapeutic target in multiple myeloma.
Grant	Targeting Dkk1 in multiple myeloma with humanized andti-DKk1 neutralizing antibody
Academic Article	Growth and dormancy control of myeloma cells by mesenchymal stem cells.

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Multiple Myeloma